Polynucleotides are purified fragments of salmon or trout DNA, and your skin reads them as a signal to heal. They activate a receptor on your own cells that switches on collagen and elastin production and improves blood supply. This is regeneration, not volume, which is why it suits thin, reactive skin so well.
They are deeply anti-inflammatory, so red, reactive skin calms down, and hydration and skin quality improve from within over the weeks after a course. Unlike a hyaluronic acid booster, they do not physically hold water. The hydration is a slower, downstream result of healthier tissue.
When scarring is tethered down, we can use a cannula to release the scar from underneath so the surface can lift. Layered with SkinPen in a single visit, the two heal together and each makes the other work better.
A medical professional consents you, numbing cream if you want it, photos for your file.
Eyes and face, or eyes, face and neck. A brief sting as it goes in, then done.
Dermalux Tri-Wave MD to settle the skin, included on memberships.
Nothing that stops your day. Avoid heat and make-up for 12 hours. Results build over the weeks after your course.
A course of two to three, two to four weeks apart, then top-ups as your skin needs them.
Prices from the live KB menu, 26 October 2026. Single sessions are paid in full. Courses can be split over three months. KB members save 10% on most further treatments and on in-clinic skincare.
It does not fight the skin, it calms it and teaches it to heal, and watching a red, reactive face settle over a few weeks never gets old. It will not correct a true hollow under the eye, that is still filler's job, and we will say so.
No. It regenerates rather than fills. For crepey, thin under-eye skin it is often the better tool, but it will not fix a true hollow.
The DNA is salmon or trout derived. A true fish or seafood allergy rules it out, so we ask directly at every consultation and reach for a gentler calming route instead.
Texture changes from two to three weeks, the fuller effect by four to eight weeks after a course, then a top-up every three to six months.
Kelsey or Aaron, our medical professionals. On a combined SkinPen visit, Louise or R-Marni needle first and your clinician follows with the polynucleotides.
Every injectable treatment at KB begins with a consultation and a prescriber's assessment. New patient assessment with Kelsey, £95. Existing patients with a plan can book straight in.
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